Again membrane proteins with specific functions (enzymes, transport proteins, receptors, etc.) are organized in the lipid bilayer in specific, asymmetric orientations. In addition, polar lipids constitute the polar lipid bilayer compartment of the plasma (and organelle) membranes of cells.
Functional apoproteins embedded in the lipid monolayer regulate lipoprotein secretion from cells, act as co-factors for lipolytic enzymes, and are involved in binding of lipoproteins to membrane receptors (see below). high density and low density lipoproteins) involved in lipid transport. First, these polar lipids provided the stabilizing lipid monolayer of the plasma lipoproteins (e.g.
Amphipathic polar lipids play a key structural role in the organization of two important classes of lipid-protein assemblies (Fig.
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